Guide on the Side: MCPHS Medline Searching: Test Yourself

Use these four sample cases to practice searching Medline database

-Log into OVID Medline

- Select Ovid MEDLINE without Revisions 1996 to 2014

-Search Medline database to solve Case #1 and print out/save your search history.

-Answer the questions related to this case to test yourself.

- Proceed to the next case and repeat the steps.

- Use the bottom arrows to proceed through this sample quiz

Case#1: Ruxolitinib is a drug recently approved by FDA for treating patients with myelofibrosis. Could you find any information on clinical trials reporting the advantages of using this medication in humans?

For the search in Medline, which of the following terms is the most appropriate to use?

Myelofibrosis Myeloproliferative Disorders Primary Myelofibrosis a+b are correct a+c are correct

Which of the following is MeSH term?

Ruxolitinib Primary Myelofibrosis Myelofibrosis a+b are correct a+b+c are correct

For the search in Medline, which terms must be combined with OR?

Myelofibrosis + Ruxolitinib Myelofibrosis + Jakafi Ruxolitinib + Jakafi a+b are correct a+c are correct

For the search in Medline, what is/are the most appropriate Limit option(s) to use?

Therapeutic Use Clinical Trial, All Humans a+b are correct b+c are correct

Click here to see the correct search history for Case #1

Case #2: A physician is trying to decide between prescribing norepinephrine and dopamine for a patient with shock in order to increase his blood pressure. Could you find any evidence in scientific literature that one of these drugs is more effective than another?

For the search in Medline, how should the terms Norepinephrine, Dopamine, Shock be combined?

Norepinephrine OR Dopamine OR Shock Norepinephrine AND Dopamine AND Shock Norepinephrine OR (Dopamine AND Shock) Norepinephrine AND (Dopamine OR Shock) All of the above are correct

For the search in Medline, which is/are the most appropriate subheadings(s) to use with the term Norepinephrine AND Dopamine?

Therapeutic Use Chemically Induced Clinical Trial, All a+b are correct b+c are correct

For the search in Medline, what is the most appropriate option to use for the term Dopamine?

Keyword MeSH term Subheading a+b are correct a+b+c are correct

For the search in Medline, what term(s) was/were exploded to include more specific terms in Medline "tree"?

Norepinephrine Dopamine Shock a+b are correct a+c are correct

Click here to see the correct search history for Case #2

Case #3: A patient with hypertension wants to know if calcium channel blockers cause cancer.

For the search in Medline, which of the following is a MeSH term for the concept Calcium Channel Blockers?

Calcium Blockers Calcium Channel Blockers CHB a+b are correct a+b+c are correct

For the search in Medline, what is the most appropriate option to use for the term Cancer?

cancer.mp. chb.mp. Neoplasms a+b are correct a+c are correct

For the search in Medline, which subheading may be useful to apply when searching for the concept of cancer?

Chemically Induced Drug Therapy Therapy a+b are correct a+c are correct

For the search in Medline, what is/are the most appropriate Limit option(s) to use?

Clinical Trial, All Humans Case Reports a+b are correct b+c are correct

Click here to see the correct search history for Case #3

Case #4: Could you find any evidence in scientific literature that supports the use of St. John's Wort in the treatment of unipolar depression?

Which of the following is a MeSH term for the concept St. John's Wort?

Saint John's Wort Hypericum St. John's Wort a+b are correct b+c are correct

Which of the following is a MeSH term for the concept Unipolar Depression?

Depressive Disorder Depression Depressive Disorder, Major a+b are correct a+b+c are correct

For the search in Medline, how should the terms be combined?

Hypericum OR St. John's Wort AND Depression Hypericum AND St. John's Wort AND Depressive Disorder Hypericum AND Depressive Disorder Depression OR St. John's Wort All of the above are correct

In Medline, what is/are the most appropriate subheading(s) to use with the MeSH term for the concept St. John's Wort?

Therapeutic Use Chemically Induced Clinical Trial, All a+b are correct b+c are correct

Click here to see the correct search history for Case #4

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